7KIE: Crystal structure of FGFR2 kinase domain gatekeeper mutant V564F in complex with covalent compound 3

PDB ID: 7KIEDownload
MMDB ID: 198662
PDB Deposition Date: 2020/10/23
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.47  Å
Source Organism:
Similar Structures:
Biological Unit for 7KIE: monomeric; determined by author and by software (PISA)
Molecular Components in 7KIE
Label Count Molecule
Protein (1 molecule)
1
Fibroblast Growth Factor Receptor 2
(Gene symbol: FGFR2)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
N-{4-[(E)-2-{4-(4-methylpiperazin-1-yl)-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl}ethenyl]phenyl}prop-2-enamideN-{4-[(E)-2-{4-(4-methylpiperazin-1-yl)-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl}ethenyl]phenyl}prop-2-enamide
2
1
CITRATE ANIONCITRATE ANION
3
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303