7KHT: The acyl chains of phosphoinositide PIP3 alter the structure and function of nuclear receptor Steroidogenic Factor-1 (SF-1)

PDB ID: 7KHTDownload
MMDB ID: 202142
PDB Deposition Date: 2020/10/22
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.504  Å
Source Organism:
Similar Structures:
Biological Unit for 7KHT: dimeric; determined by author and by software (PISA)
Molecular Components in 7KHT
Label Count Molecule
Proteins (2 molecules)
1
Steroidogenic Factor 1
(Gene symbol: NR5A1)
Molecule annotation
1
Peroxisome Proliferator-activated Receptor Gamma Coactivator 1-alpha Peptide
(Gene symbol: PPARGC1A)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(2S)-3-{[(S)-{[(1S,2S,3R,4S,5S,6S)-2,6-dihydroxy-3,4,5-tris(phosphonooxy)cyclohexyl]oxy}(hydroxy)phosphoryl]oxy}propane-1,2-diyl (9E,9'E)di-octadec-9-enoate(2S)-3-{[(S)-{[(1S,2S,3R,4S,5S,6S)-2,6-dihydroxy-3,4,5-tris(phosphonooxy)cyclohexyl]oxy}(hydroxy)phosphoryl]oxy}propane-1,2-diyl (9E,9'E)di-octadec-9-enoate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303