7KHG: Crystal structure of KIT kinase domain with a small molecule inhibitor, PLX3397

PDB ID: 7KHGDownload
MMDB ID: 204101
PDB Deposition Date: 2020/10/21
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.15  Å
Source Organism:
Similar Structures:
Biological Unit for 7KHG: monomeric; determined by software (PISA)
Molecular Components in 7KHG
Label Count Molecule
Protein (1 molecule)
1
Mast/stem Cell Growth Factor Receptor KIT
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
5-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-N-{[6-(trifluoromethyl)pyridin-3-yl]methyl}pyridin-2-amine5-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-N-{[6-(trifluoromethyl)pyridin-3-yl]methyl}pyridin-2-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303