7KDR: Crystal structure of Escherichia coli HPPK in complex with bisubstrate inhibitor HP-75

PDB ID: 7KDRDownload
MMDB ID: 196034
PDB Deposition Date: 2020/10/9
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.488  Å
Source Organism:
Similar Structures:
Biological Unit for 7KDR: monomeric; determined by author and by software (PISA)
Molecular Components in 7KDR
Label Count Molecule
Protein (1 molecule)
1
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine Pyrophosphokinase
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
5'-{[(2R,4R)-1-{2-[(2-amino-7,7-dimethyl-4-oxo-3,4,7,8-tetrahydropteridine-6-carbonyl)amino]ethyl}-2-carboxypiperidin-4-yl]sulfonyl}-5'-deoxyadenosine5'-{[(2R,4R)-1-{2-[(2-amino-7,7-dimethyl-4-oxo-3,4,7,8-tetrahydropteridine-6-carbonyl)amino]ethyl}-2-carboxypiperidin-4-yl]sulfonyl}-5'-deoxyadenosine
2
1
CHLORIDE IONCHLORIDE ION
3
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303