7KBH: Structure of Human HDAC2 in complex with a 2-substituted benzamide inhibitor (compound 16)

PDB ID: 7KBHDownload
MMDB ID: 197080
PDB Deposition Date: 2020/10/2
Updated in MMDB: 2024/03
Experimental Method:
x-ray diffraction
Resolution: 2.68  Å
Source Organism:
Similar Structures:
Biological Unit for 7KBH: monomeric; determined by author and by software (PISA)
Molecular Components in 7KBH
Label Count Molecule
Protein (1 molecule)
1
Histone Deacetylase 2
(Gene symbol: HDAC2)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
1
ZINC IONZINC ION
2
2
CALCIUM IONCALCIUM ION
3
3
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
4
1
N-{(1S)-5-{[2-(methylsulfanyl)benzene-1-carbonyl]amino}-1-[5-(naphthalen-2-yl)-1H-imidazol-2-yl]pentyl}-1,3-thiazole-5-carboxamideN-{(1S)-5-{[2-(methylsulfanyl)benzene-1-carbonyl]amino}-1-[5-(naphthalen-2-yl)-1H-imidazol-2-yl]pentyl}-1,3-thiazole-5-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303