7K9A: Crystal Structure of P. aeruginosa LpxC with N-Hydroxyformamide inhibitor

PDB ID: 7K9ADownload
MMDB ID: 195721
PDB Deposition Date: 2020/9/29
Updated in MMDB: 2020/12
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 7K9A: monomeric; determined by author and by software (PISA)
Molecular Components in 7K9A
Label Count Molecule
Protein (1 molecule)
1
Udp-3-o-acyl-n-acetylglucosamine Deacetylase
(Gene symbol: lpxC)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
N-hydroxy-N-[(1S)-2-{5-[(4-{[2-(hydroxymethyl)-1H-imidazol-1-yl]methyl}phenyl)ethynyl]-1H-benzotriazol-1-yl}-1-(methylsulfanyl)ethyl]formamideN-hydroxy-N-[(1S)-2-{5-[(4-{[2-(hydroxymethyl)-1H-imidazol-1-yl]methyl}phenyl)ethynyl]-1H-benzotriazol-1-yl}-1-(methylsulfanyl)ethyl]formamide
2
1
SULFATE IONSULFATE ION
3
2
GLYCEROLGLYCEROL
4
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
5
1
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303