7K71: Crystal structure of PI3Kalpha inhibitor 4-0686

PDB ID: 7K71Download
MMDB ID: 197164
PDB Deposition Date: 2020/9/21
Updated in MMDB: 2024/04
Experimental Method:
x-ray diffraction
Resolution: 2.9  Å
Source Organism:
Similar Structures:
Biological Unit for 7K71: monomeric; determined by author and by software (PISA)
Molecular Components in 7K71
Label Count Molecule
Protein (1 molecule)
1
Phosphatidylinositol 4,5-bisphosphate 3-kinase Catalytic Subunit Alpha Isoform
(Gene symbol: PIK3CA)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
2-(morpholin-4-yl)[4,5'-bipyrimidin]-2'-amine2-(morpholin-4-yl)[4,5'-bipyrimidin]-2'-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303