7K65: Hedgehog receptor Patched (PTCH1) in complex with conformation selective nanobody TI23

PDB ID: 7K65Download
MMDB ID: 199968
PDB Deposition Date: 2020/9/18
Updated in MMDB: 2024/12
Experimental Method:
electron microscopy
Resolution: 3.4  Å
Source Organism:
Mus musculus▼
Similar Structures:
Biological Unit for 7K65: dimeric; determined by author
Molecular Components in 7K65
Label Count Molecule
Proteins (2 molecules)
1
Protein Patched Homolog 1
Molecule annotation
1
Nanobody Ti23
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
7
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
4
2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303