7K15: Crystal structure of the Human Leukotriene B4 Receptor 1 in Complex with Selective Antagonist MK-D-046

PDB ID: 7K15Download
MMDB ID: 198978
PDB Deposition Date: 2020/9/7
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.88  Å
Source Organism:
Similar Structures:
Biological Unit for 7K15: monomeric; determined by author
Molecular Components in 7K15
Label Count Molecule
Protein (1 molecule)
1
Leukotriene B4 Receptor 1,flavodoxin,leukotriene B4 Receptor 1
(Gene symbol: LTB4R)
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
1
N-(tert-butylsulfonyl)-4-fluoro-2-{(3S,4R)-4-hydroxy-3-[(pyridin-2-yl)methyl]-3,4-dihydro-2H-1-benzopyran-7-yl}benzamideN-(tert-butylsulfonyl)-4-fluoro-2-{(3S,4R)-4-hydroxy-3-[(pyridin-2-yl)methyl]-3,4-dihydro-2H-1-benzopyran-7-yl}benzamide
2
1
SODIUM IONSODIUM ION
3
1
FLAVIN MONONUCLEOTIDEFLAVIN MONONUCLEOTIDE
4
1
OLEIC ACIDOLEIC ACID
5
2
(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
6
1
PENTAETHYLENE GLYCOLPENTAETHYLENE GLYCOL
7
1
NONAETHYLENE GLYCOLNONAETHYLENE GLYCOL
8
1
HEXAETHYLENE GLYCOLHEXAETHYLENE GLYCOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303