7K0Q: Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, myriocin-bound

PDB ID: 7K0QDownload
MMDB ID: 199148
PDB Deposition Date: 2020/9/4
Updated in MMDB: 2025/05
Experimental Method:
electron microscopy
Resolution: 3.3  Å
Source Organism:
Similar Structures:
Biological Unit for 7K0Q: tetrameric; determined by author
Molecular Components in 7K0Q
Label Count Molecule
Proteins (4 molecules)
1
Serine Palmitoyltransferase 1
(Gene symbol: SPTLC1)
Molecule annotation
1
Serine Palmitoyltransferase 2
(Gene symbol: SPTLC2)
Molecule annotation
1
Serine Palmitoyltransferase Small Subunit a
(Gene symbol: SPTSSA)
Molecule annotation
1
Orm1-like Protein 3
(Gene symbol: ORMDL3)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
PYRIDOXAL-5'-PHOSPHATEPYRIDOXAL-5'-PHOSPHATE
2
1
MyriocinMyriocin
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303