7K0H: 1.70 A resolution structure of SARS-CoV 3CL protease in complex with a deuterated GC376 alpha-ketoamide analog (compound 5)

PDB ID: 7K0HDownload
MMDB ID: 204100
PDB Deposition Date: 2020/9/4
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.7  Å
Source Organism:
Similar Structures:
Biological Unit for 7K0H: dimeric; determined by author and by software (PISA)
Molecular Components in 7K0H
Label Count Molecule
Proteins (2 molecules)
2
Replicase Polyprotein 1A
(Gene symbol: orf1ab)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
2
CHLORIDE IONCHLORIDE ION
2
2
N-{(2S,3R)-4-(benzylamino)-3-hydroxy-4-oxo-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl}-N~2~-[(benzyloxy)carbonyl]-L-leucinamideN-{(2S,3R)-4-(benzylamino)-3-hydroxy-4-oxo-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl}-N~2~-[(benzyloxy)carbonyl]-L-leucinamide
3
1
TETRAETHYLENE GLYCOLTETRAETHYLENE GLYCOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303