7JYM: CRYSTAL STRUCTURE OF RAR-RELATED ORPHAN RECEPTOR C (NHIS-RORGT(244-487)-L6-SRC1(678-692)) IN COMPLEX WITH A TRICYCLIC SULFONE INVERSE AGONIST

PDB ID: 7JYMDownload
MMDB ID: 195711
PDB Deposition Date: 2020/8/31
Updated in MMDB: 2020/12
Experimental Method:
x-ray diffraction
Resolution: 3.051  Å
Source Organism:
Similar Structures:
Biological Unit for 7JYM: monomeric; determined by author and by software (PISA)
Molecular Components in 7JYM
Label Count Molecule
Protein (1 molecule)
1
Nuclear Receptor Ror-gamma, Nuclear Receptor Coactivator 1
(Gene symbol: RORC)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(3R,5S)-3-fluoro-5-[(3aR,9bR)-9b-[(4-fluorophenyl)sulfonyl]-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-1,2,3a,4,5,9b-hexahydro-3H-benzo[e]indole-3-carbonyl]-1-(2-hydroxy-2-methylpropyl)pyrrolidin-2-one(3R,5S)-3-fluoro-5-[(3aR,9bR)-9b-[(4-fluorophenyl)sulfonyl]-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-1,2,3a,4,5,9b-hexahydro-3H-benzo[e]indole-3-carbonyl]-1-(2-hydroxy-2-methylpropyl)pyrrolidin-2-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303