7JXH: HER2 in complex with JBJ-08-178-01

PDB ID: 7JXHDownload
MMDB ID: 206323
PDB Deposition Date: 2020/8/27
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 3.27  Å
Source Organism:
Similar Structures:
Biological Unit for 7JXH: monomeric; determined by author and by software (PISA)
Molecular Components in 7JXH
Label Count Molecule
Protein (1 molecule)
1
Receptor Tyrosine-protein Kinase Erbb-2
(Gene symbol: ERBB2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(2E)-N-[3-cyano-7-ethoxy-4-({3-methyl-4-[([1,2,4]triazolo[1,5-a]pyridin-7-yl)oxy]phenyl}amino)quinolin-6-yl]-4-(dimethylamino)but-2-enamide(2E)-N-[3-cyano-7-ethoxy-4-({3-methyl-4-[([1,2,4]triazolo[1,5-a]pyridin-7-yl)oxy]phenyl}amino)quinolin-6-yl]-4-(dimethylamino)but-2-enamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303