7JX9: The crystal structure of human ornithine aminotransferase with an intermediate bound during inactivation by (1S,3S)-3-amino-4-(hexafluoropropan-2-ylidenyl)-cyclopentane-1-carboxylic acid

PDB ID: 7JX9Download
MMDB ID: 197151
PDB Deposition Date: 2020/8/26
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.96  Å
Source Organism:
Similar Structures:
Biological Unit for 7JX9: dimeric; determined by author and by software (PISA)
Molecular Components in 7JX9
Label Count Molecule
Proteins (2 molecules)
2
Ornithine Aminotransferase, Mitochondrial
(Gene symbol: OAT)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
(1S,3S,4S)-3-[(E)-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)amino]-4-(1,1,3,3,3-pentafluoroprop-1-en-2-yl)cyclopentane-1-carboxylic acid(1S,3S,4S)-3-[(E)-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)amino]-4-(1,1,3,3,3-pentafluoroprop-1-en-2-yl)cyclopentane-1-carboxylic acid
2
4
N-[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]glycineN-[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]glycine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303