7JWW: Crystal structure of human ALDH1A1 bound to compound (R)-28

PDB ID: 7JWWDownload
MMDB ID: 197073
PDB Deposition Date: 2020/8/26
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.6  Å
Source Organism:
Similar Structures:
Biological Unit for 7JWW: tetrameric; determined by author and by software (PISA)
Molecular Components in 7JWW
Label Count Molecule
Proteins (4 molecules)
4
Retinal Dehydrogenase 1
(Gene symbol: ALDH1A1)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
4
5-{4-[(Z)-2-hydroxyethenyl]phenyl}-1-methyl-6-{[(1R)-1-phenylethyl]sulfanyl}-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one5-{4-[(Z)-2-hydroxyethenyl]phenyl}-1-methyl-6-{[(1R)-1-phenylethyl]sulfanyl}-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one
2
4
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303