7JVV: Crystal structure of human histone deacetylase 8 (HDAC8) E66D/Y306F double mutation complexed with a tetrapeptide substrate

PDB ID: 7JVVDownload
MMDB ID: 196637
PDB Deposition Date: 2020/8/24
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.84  Å
Source Organism:
Similar Structures:
Biological Unit for 7JVV: trimeric; determined by author and by software (PISA)
Molecular Components in 7JVV
Label Count Molecule
Protein (1 molecule)
1
Histone Deacetylase 8
(Gene symbol: HDAC8)
Molecule annotation
Chemicals and Non-standard biopolymers (18 molecules)
CD
2
ACE-ARG-HIS-ALY-ALY-MCM
1
8
1,2-ETHANEDIOL1,2-ETHANEDIOL
2
2
ZINC IONZINC ION
3
4
POTASSIUM IONPOTASSIUM ION
4
2
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303