7JVU: Crystal structure of human histone deacetylase 8 (HDAC8) I45T mutation complexed with SAHA

PDB ID: 7JVUDownload
MMDB ID: 196636
PDB Deposition Date: 2020/8/24
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.50048  Å
Source Organism:
Similar Structures:
Biological Unit for 7JVU: monomeric; determined by author
Molecular Components in 7JVU
Label Count Molecule
Protein (1 molecule)
1
Histone Deacetylase 8
(Gene symbol: HDAC8)
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
1
ZINC IONZINC ION
2
2
POTASSIUM IONPOTASSIUM ION
3
2
OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDEOCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE
4
4
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303