7JVP: Cryo-EM structure of SKF-83959-bound dopamine receptor 1 in complex with Gs protein

PDB ID: 7JVPDownload
MMDB ID: 199137
PDB Deposition Date: 2020/8/22
Updated in MMDB: 2025/05
Experimental Method:
electron microscopy
Resolution: 2.9  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 7JVP: pentameric; determined by author
Molecular Components in 7JVP
Label Count Molecule
Proteins (5 molecules)
1
D(1a) Dopamine Receptor
Molecule annotation
1
Guanine Nucleotide-binding Protein G(s) Subunit Alpha Isoforms Short
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
Molecule annotation
1
Nanobody 35
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
1
(1R)-6-chloro-3-methyl-1-(3-methylphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol(1R)-6-chloro-3-methyl-1-(3-methylphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol
2
6
CHOLESTEROLCHOLESTEROL
3
5
PALMITIC ACIDPALMITIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303