7JU5: Structure of RET protein tyrosine kinase in complex with pralsetinib

PDB ID: 7JU5Download
MMDB ID: 195179
PDB Deposition Date: 2020/8/19
Updated in MMDB: 2020/12
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 7JU5: dimeric; determined by author and by software (PISA)
Molecular Components in 7JU5
Label Count Molecule
Proteins (2 molecules)
2
Proto-oncogene Tyrosine-protein Kinase Receptor RET
(Gene symbol: RET)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
PralsetinibPralsetinib
2
4
FORMIC ACIDFORMIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303