7JTT: The external aldimine crystal structure of Salmonella typhimurium Tryptophan Synthase mutant beta-S377A in complex F9 inhibitor at the alpha-site and cesium ion at the metal coordination site. The single beta-Q114 rotamer conformation allows a hydrogen bo

PDB ID: 7JTTDownload
MMDB ID: 205885
PDB Deposition Date: 2020/8/18
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.64  Å
Source Organism:
Similar Structures:
Biological Unit for 7JTT: dimeric; determined by author
Molecular Components in 7JTT
Label Count Molecule
Proteins (2 molecules)
1
Tryptophan Synthase Alpha Chain
(Gene symbol: trpA)
Molecule annotation
1
Tryptophan Synthase Beta Chain
(Gene symbol: trpB)
Molecule annotation
Chemicals and Non-standard biopolymers (40 molecules)
1
1
2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE
2
24
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
3
4
CHLORIDE IONCHLORIDE ION
4
1
(E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-serine(E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-serine
5
1
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
6
7
1,2-ETHANEDIOL1,2-ETHANEDIOL
7
2
CESIUM IONCESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303