7JSP: Crystal structure of the second bromodomain (BD2) of human TAF1 bound to ATR kinase inhibitor AZD6738

PDB ID: 7JSPDownload
MMDB ID: 205883
PDB Deposition Date: 2020/8/15
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.7  Å
Source Organism:
Similar Structures:
Biological Unit for 7JSP: monomeric; determined by author and by software (PISA)
Molecular Components in 7JSP
Label Count Molecule
Protein (1 molecule)
1
Transcription Initiation Factor Tfiid Subunit 1
(Gene symbol: TAF1)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
4-(4-{1-[(R)-amino(hydroxy)methyl-lambda~4~-sulfanyl]cyclopropyl}-6-[(3R)-3-methylmorpholin-4-yl]pyrimidin-2-yl)-1H-pyrrolo[2,3-b]pyridine4-(4-{1-[(R)-amino(hydroxy)methyl-lambda~4~-sulfanyl]cyclopropyl}-6-[(3R)-3-methylmorpholin-4-yl]pyrimidin-2-yl)-1H-pyrrolo[2,3-b]pyridine
2
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
1
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303