7JR8: H-PDGS complexed with a 2-phenylimidazo[1,2-a]pyridine-6-carboxamide inhibitors

PDB ID: 7JR8Download
MMDB ID: 202461
PDB Deposition Date: 2020/8/11
Updated in MMDB: 2021/07
Experimental Method:
x-ray diffraction
Resolution: 1.13  Å
Source Organism:
Similar Structures:
Biological Unit for 7JR8: dimeric; determined by author and by software (PISA)
Molecular Components in 7JR8
Label Count Molecule
Proteins (2 molecules)
2
Hematopoietic Prostaglandin D Synthase
(Gene symbol: HPGDS)
Molecule annotation
Chemicals and Non-standard biopolymers (13 molecules)
1
1
CHLORIDE IONCHLORIDE ION
2
3
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
2
GLUTATHIONEGLUTATHIONE
4
2
N-[trans-4-(2-hydroxypropan-2-yl)cyclohexyl]-2-phenylimidazo[1,2-a]pyridine-6-carboxamideN-[trans-4-(2-hydroxypropan-2-yl)cyclohexyl]-2-phenylimidazo[1,2-a]pyridine-6-carboxamide
5
2
MAGNESIUM IONMAGNESIUM ION
6
3
SODIUM IONSODIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303