7JOV: CRYSTAL STRUCTURE OF RHO-ASSOCIATED PROTEIN KINASE 2 (ROCK2) IN COMPLEX WITH A PHENYLPYRAZOLE AMIDE INHIBITOR

PDB ID: 7JOVDownload
MMDB ID: 192033
PDB Deposition Date: 2020/8/7
Updated in MMDB: 2020/09
Experimental Method:
x-ray diffraction
Resolution: 2.586  Å
Source Organism:
Similar Structures:
Biological Unit for 7JOV: dimeric; determined by software (PISA)
Molecular Components in 7JOV
Label Count Molecule
Proteins (2 molecules)
2
Rho-associated Protein Kinase 2
(Gene symbol: ROCK2)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
2-(N-MORPHOLINO)-ETHANESULFONIC ACID2-(N-MORPHOLINO)-ETHANESULFONIC ACID
2
2
N-[(1S)-2-hydroxy-1-phenylethyl]-3-methoxy-4-(1H-pyrazol-4-yl)benzamideN-[(1S)-2-hydroxy-1-phenylethyl]-3-methoxy-4-(1H-pyrazol-4-yl)benzamide
3
1
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303