7JMQ: The external aldimine form of the mutant beta-S377A Salmonella thypi tryptophan synthase in open conformation showing dual side chain conformations for the residue beta-Q114, sodium ion at the metal coordination site, and F9 inhibitor at the alpha-site. O

PDB ID: 7JMQDownload
MMDB ID: 205235
PDB Deposition Date: 2020/8/2
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.6  Å
Source Organism:
Similar Structures:
Biological Unit for 7JMQ: tetrameric; determined by author
Molecular Components in 7JMQ
Label Count Molecule
Proteins (4 molecules)
2
Tryptophan Synthase Alpha Chain
(Gene symbol: trpA)
Molecule annotation
2
Tryptophan Synthase Beta Chain
(Gene symbol: trpB)
Molecule annotation
Chemicals and Non-standard biopolymers (86 molecules)
1
66
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
2
2
2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE
3
4
CESIUM IONCESIUM ION
4
2
(E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-serine(E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-serine
5
4
GLYCEROLGLYCEROL
6
4
1,2-ETHANEDIOL1,2-ETHANEDIOL
7
2
SODIUM IONSODIUM ION
8
2
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303