7JL8: Human PrimPol extending from the correct primer base C opposite the 8-oxoguanine lesion

PDB ID: 7JL8Download
MMDB ID: 203786
PDB Deposition Date: 2020/7/29
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 7JL8: trimeric; determined by author
Molecular Components in 7JL8
Label Count Molecule
Protein (1 molecule)
1
DNA-directed Primase/polymerase Protein
Molecule annotation
Nucleotides(2 molecules)
1
DNA (5'-d(p*ap*tp*(8og)p*cp*cp*tp*ap*cp*cp*ap*cp*a)-3')
Molecule annotation
1
DNA (5'-d(p*gp*tp*gp*gp*tp*ap*gp*gp*c)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
1
2'-DEOXYADENOSINE 5'-TRIPHOSPHATE2'-DEOXYADENOSINE 5'-TRIPHOSPHATE
2
1
CALCIUM IONCALCIUM ION
3
2
GLYCEROLGLYCEROL
4
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
5
2
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303