7JL0: Cryo-EM structure of MDA5-dsRNA in complex with TRIM65 PSpry domain (Monomer)

PDB ID: 7JL0Download
MMDB ID: 196256
PDB Deposition Date: 2020/7/29
Updated in MMDB: 2024/03
Experimental Method:
electron microscopy
Resolution: 4.3  Å
Source Organism:
Similar Structures:
Biological Unit for 7JL0: tetrameric; determined by author
Molecular Components in 7JL0
Label Count Molecule
Proteins (2 molecules)
1
Interferon-induced Helicase C Domain-containing Protein 1
(Gene symbol: IFIH1)
Molecule annotation
1
Tripartite Motif-containing Protein 65
(Gene symbol: TRIM65)
Molecule annotation
Nucleotides(2 molecules)
1
RNA (5'-r(p*gp*ap*cp*up*gp*ap*cp*up*gp*ap*cp*up*gp*a)-3')
Molecule annotation
1
RNA (5'-r(p*up*cp*ap*gp*up*cp*ap*gp*up*cp*ap*gp*up*c)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
ZINC IONZINC ION
2
1
ADENOSINE-5'-DIPHOSPHATEADENOSINE-5'-DIPHOSPHATE
3
1
TETRAFLUOROALUMINATE IONTETRAFLUOROALUMINATE ION
4
1
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303