7JHW: The internal aldimine crystal structure of Salmonella typhimurium Tryptophan Synthase mutant beta-S377A in complex with inhibitor 2-({[4-(trifluoromethoxy)phenyl]sulfonyl}amino)ethyl dihydrogen phosphate (F9F) at the alpha-site and Cesium ion at the metal

PDB ID: 7JHWDownload
MMDB ID: 204927
PDB Deposition Date: 2020/7/21
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.65  Å
Source Organism:
Similar Structures:
Biological Unit for 7JHW: tetrameric; determined by author and by software (PISA)
Molecular Components in 7JHW
Label Count Molecule
Proteins (4 molecules)
2
Tryptophan Synthase Alpha Chain
(Gene symbol: trpA)
Molecule annotation
2
Tryptophan Synthase Beta Chain
(Gene symbol: trpB)
Molecule annotation
Chemicals and Non-standard biopolymers (68 molecules)
1
2
2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE
2
40
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
3
18
CHLORIDE IONCHLORIDE ION
4
2
PYRIDOXAL-5'-PHOSPHATEPYRIDOXAL-5'-PHOSPHATE
5
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
6
4
CESIUM IONCESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303