7HKE: Group deposition for crystallographic fragment screening of the NS5 RNA-dependent RNA polymerase from Dengue virus serotype 2 -- Crystal structure of the NS5 RNA-dependent RNA polymerase from Dengue virus serotype 2 in complex with Z53860899 (DNV2_NS5A-x0

PDB ID: 7HKEDownload
MMDB ID: 254059
PDB Deposition Date: 2024/10/15
Updated in MMDB: 2024/11
Experimental Method:
x-ray diffraction
Resolution: 1.64  Å
Source Organism:
Similar Structures:
Biological Unit for 7HKE: monomeric; determined by author
Molecular Components in 7HKE
Label Count Molecule
Protein (1 molecule)
1
Genome Polyprotein
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
2
ZINC IONZINC ION
2
1
2-(N-MORPHOLINO)-ETHANESULFONIC ACID2-(N-MORPHOLINO)-ETHANESULFONIC ACID
3
3
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
4
3
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
5
2
PHOSPHATE IONPHOSPHATE ION
6
1
~{N}-(1,3-benzodioxol-5-ylmethyl)ethanesulfonamide~{N}-(1,3-benzodioxol-5-ylmethyl)ethanesulfonamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303