7H42: Group deposition for crystallographic fragment screening of Coxsackievirus A16 (G-10) 2A protease -- Crystal structure of Coxsackievirus A16 (G-10) 2A protease in complex with Z124039706 (A71EV2A-x0540)

PDB ID: 7H42Download
MMDB ID: 245682
PDB Deposition Date: 2024/4/4
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 1.24  Å
Source Organism:
Similar Structures:
Biological Unit for 7H42: monomeric; determined by author and by software (PISA)
Molecular Components in 7H42
Label Count Molecule
Protein (1 molecule)
1
Protease 2A
(Gene symbol: HEVAgp1)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
1
4-({[(4-fluorophenyl)methyl]amino}methyl)benzonitrile4-({[(4-fluorophenyl)methyl]amino}methyl)benzonitrile
2
1
ZINC IONZINC ION
3
4
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
4
1
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303