7G8R: ARHGEF2 PanDDA analysis group deposition -- ARHGEF2 and RhoA in complex with Z1270087714

PDB ID: 7G8RDownload
MMDB ID: 232603
PDB Deposition Date: 2023/6/22
Updated in MMDB: 2023/07
Experimental Method:
x-ray diffraction
Resolution: 1.44  Å
Source Organism:
Similar Structures:
Biological Unit for 7G8R: dimeric; determined by author and by software (PISA)
Molecular Components in 7G8R
Label Count Molecule
Proteins (2 molecules)
1
Transforming Protein Rhoa
(Gene symbol: RHOA)
Molecule annotation
1
RHO Guanine Nucleotide Exchange Factor 2
(Gene symbol: ARHGEF2)
Molecule annotation
Chemicals and Non-standard biopolymers (19 molecules)
1
1
(2R,6S)-2,6-dimethyl-4-(3-methyl-1,2,4-thiadiazol-5-yl)morpholine(2R,6S)-2,6-dimethyl-4-(3-methyl-1,2,4-thiadiazol-5-yl)morpholine
2
5
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
3
13
FORMIC ACIDFORMIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303