7G02: Crystal Structure of human FABP4 in complex with 7-methoxy-1-(3-methoxyphenyl)naphthalene-2-carboxylic acid, i.e. SMILES c1(c2c(ccc1C(=O)O)ccc(c2)OC)c1cc(ccc1)OC with IC50=0.045 microM

PDB ID: 7G02Download
MMDB ID: 231413
PDB Deposition Date: 2023/4/27
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 1.03  Å
Source Organism:
Similar Structures:
Biological Unit for 7G02: monomeric; determined by author and by software (PISA)
Molecular Components in 7G02
Label Count Molecule
Protein (1 molecule)
1
Fatty Acid-binding Protein, Adipocyte
(Gene symbol: FABP4)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
(1M)-7-methoxy-1-(3-methoxyphenyl)naphthalene-2-carboxylic acid(1M)-7-methoxy-1-(3-methoxyphenyl)naphthalene-2-carboxylic acid
2
1
SULFATE IONSULFATE ION
3
1
FORMIC ACIDFORMIC ACID
4
1
TETRAETHYLENE GLYCOLTETRAETHYLENE GLYCOL
5
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303