7G01: Crystal Structure of human FABP5 in complex with 6-chloro-4-phenyl-2-piperidin-1-ylquinoline-3-carboxylic acid, i.e. SMILES n1c(c(c(c2c1ccc(c2)Cl)c1ccccc1)C(=O)O)N1CCCCC1 with IC50=1.1 microM

PDB ID: 7G01Download
MMDB ID: 231412
PDB Deposition Date: 2023/4/27
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 1.17  Å
Source Organism:
Similar Structures:
Biological Unit for 7G01: monomeric; determined by author and by software (PISA)
Molecular Components in 7G01
Label Count Molecule
Protein (1 molecule)
1
Fatty Acid-binding Protein 5
(Gene symbol: FABP5)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
2
1
SULFATE IONSULFATE ION
3
2
6-chloranyl-4-phenyl-2-piperidin-1-yl-quinoline-3-carboxylic acid6-chloranyl-4-phenyl-2-piperidin-1-yl-quinoline-3-carboxylic acid
4
1
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303