7FYI: Crystal Structure of human FABP4 in complex with 5-[(4-chlorophenyl)sulfanylmethyl]-2-methylpyrazol-3-ol, i.e. SMILES C1(=CC(=NN1C)CSc1ccc(cc1)Cl)O with IC50=17 microM

PDB ID: 7FYIDownload
MMDB ID: 231358
PDB Deposition Date: 2023/4/27
Updated in MMDB: 2024/11
Experimental Method:
x-ray diffraction
Resolution: 1.14  Å
Source Organism:
Similar Structures:
Biological Unit for 7FYI: monomeric; determined by author and by software (PISA)
Molecular Components in 7FYI
Label Count Molecule
Protein (1 molecule)
1
Fatty Acid-binding Protein, Adipocyte
(Gene symbol: FABP4)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
SULFATE ION (Link to PubChem not yet available)SULFATE ION
2
1
(5R)-3-{[(4-chlorophenyl)sulfanyl]methyl}-1-methyl-4,5-dihydro-1H-pyrazol-5-ol (Link to PubChem not yet available)(5R)-3-{[(4-chlorophenyl)sulfanyl]methyl}-1-methyl-4,5-dihydro-1H-pyrazol-5-ol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303