7FY0: Crystal Structure of human FABP5 in complex with (2R)-1-[(3,5-dichloro-2-phenylphenyl)carbamoyl]pyrrolidine-2-carboxylic acid, i.e. SMILES c1(cc(cc(c1c1ccccc1)Cl)Cl)NC(=O)N1CCC[C@@H]1C(=O)O with IC50=18 microM

PDB ID: 7FY0Download
MMDB ID: 231340
PDB Deposition Date: 2023/4/27
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 1.34  Å
Source Organism:
Similar Structures:
Biological Unit for 7FY0: monomeric; determined by author and by software (PISA)
Molecular Components in 7FY0
Label Count Molecule
Protein (1 molecule)
1
Fatty Acid-binding Protein 5
(Gene symbol: FABP5)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
2
3
SULFATE IONSULFATE ION
3
1
1-[(4,6-dichloro[1,1'-biphenyl]-2-yl)carbamoyl]-D-proline1-[(4,6-dichloro[1,1'-biphenyl]-2-yl)carbamoyl]-D-proline
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303