7FXB: Crystal Structure of human FABP4 in complex with 2-methyl-2-(2,3,4,5,6-pentachlorophenoxy)propanoic acid, i.e. SMILES C(C(=O)O)(Oc1c(c(c(c(c1Cl)Cl)Cl)Cl)Cl)(C)C with IC50=0.087 microM

PDB ID: 7FXBDownload
MMDB ID: 231315
PDB Deposition Date: 2023/4/27
Updated in MMDB: 2024/11
Experimental Method:
x-ray diffraction
Resolution: 1.12  Å
Source Organism:
Similar Structures:
Biological Unit for 7FXB: monomeric; determined by author and by software (PISA)
Molecular Components in 7FXB
Label Count Molecule
Protein (1 molecule)
1
Fatty Acid-binding Protein, Adipocyte
(Gene symbol: FABP4)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
FORMIC ACID (Link to PubChem not yet available)FORMIC ACID
2
1
SULFATE ION (Link to PubChem not yet available)SULFATE ION
3
1
2-methyl-2-(pentachlorophenoxy)propanoic acid (Link to PubChem not yet available)2-methyl-2-(pentachlorophenoxy)propanoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303