7FX1: Crystal Structure of human FABP4 in complex with 2-(3-phenyl-4-piperidin-1-ylphenyl)acetic acid, i.e. SMILES c1(c(N2CCCCC2)ccc(c1)CC(=O)O)c1ccccc1 with IC50=0.252291 microM

PDB ID: 7FX1Download
MMDB ID: 231305
PDB Deposition Date: 2023/4/27
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 0.99  Å
Source Organism:
Similar Structures:
Biological Unit for 7FX1: monomeric; determined by author and by software (PISA)
Molecular Components in 7FX1
Label Count Molecule
Protein (1 molecule)
1
Fatty Acid-binding Protein, Adipocyte
(Gene symbol: FABP4)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
[6-(piperidin-1-yl)[1,1'-biphenyl]-3-yl]acetic acid[6-(piperidin-1-yl)[1,1'-biphenyl]-3-yl]acetic acid
2
2
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303