7FW7: Crystal Structure of human FABP4 in complex with 2-[(3-chloro-4-fluorophenyl)carbamoyl]cyclohexane-1-carboxylic acid, i.e. SMILES C(=O)([C@H]1[C@@H](C(=O)O)CCCC1)Nc1cc(c(cc1)F)Cl with IC50=12.0427 microM

PDB ID: 7FW7Download
MMDB ID: 231275
PDB Deposition Date: 2023/4/27
Updated in MMDB: 2024/11
Experimental Method:
x-ray diffraction
Resolution: 1.06  Å
Source Organism:
Similar Structures:
Biological Unit for 7FW7: monomeric; determined by author and by software (PISA)
Molecular Components in 7FW7
Label Count Molecule
Protein (1 molecule)
1
Fatty Acid-binding Protein, Adipocyte
(Gene symbol: FABP4)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
(1S,2S)-2-[(3-chloro-4-fluorophenyl)carbamoyl]cyclohexane-1-carboxylic acid (Link to PubChem not yet available)(1S,2S)-2-[(3-chloro-4-fluorophenyl)carbamoyl]cyclohexane-1-carboxylic acid
2
2
SULFATE ION (Link to PubChem not yet available)SULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303