7FTR: Crystal Structure of human cyclic GMP-AMP synthase in complex with (Z)-N-(4-acetylphenyl)-2-cyano-3-hydroxy-3-(5-methyl-1,2-oxazol-4-yl)prop-2-enamide

PDB ID: 7FTRDownload
MMDB ID: 242835
PDB Deposition Date: 2023/2/8
Updated in MMDB: 2026/02
Experimental Method:
x-ray diffraction
Resolution: 1.64  Å
Source Organism:
Similar Structures:
Biological Unit for 7FTR: monomeric; determined by author
Molecular Components in 7FTR
Label Count Molecule
Protein (1 molecule)
1
Cyclic Gmp-amp Synthase
(Gene symbol: CGAS)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
ZINC IONZINC ION
2
2
MAGNESIUM IONMAGNESIUM ION
3
1
ADENOSINE-5'-TRIPHOSPHATEADENOSINE-5'-TRIPHOSPHATE
4
1
SULFATE IONSULFATE ION
5
1
(2Z)-N-(4-acetylphenyl)-2-cyano-3-hydroxy-3-(5-methyl-1,2-oxazol-4-yl)prop-2-enamide(2Z)-N-(4-acetylphenyl)-2-cyano-3-hydroxy-3-(5-methyl-1,2-oxazol-4-yl)prop-2-enamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303