7FTN: Crystal Structure of human cyclic GMP-AMP synthase in complex with propanedioic acid

PDB ID: 7FTNDownload
MMDB ID: 242831
PDB Deposition Date: 2023/2/8
Updated in MMDB: 2026/02
Experimental Method:
x-ray diffraction
Resolution: 2.001  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 7FTN: trimeric; determined by author
Molecular Components in 7FTN
Label Count Molecule
Protein (1 molecule)
1
Cyclic Gmp-amp Synthase
Molecule annotation
Nucleotides(2 molecules)
1
DNA (5'-d(*ap*ap*ap*tp*tp*gp*cp*cp*gp*ap*ap*gp*ap*cp*gp*a)-3')
Molecule annotation
1
DNA (5'-d(*tp*cp*gp*tp*cp*tp*tp*cp*gp*gp*cp*ap*ap*tp*t)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
ZINC IONZINC ION
2
1
MALONATE IONMALONATE ION
3
1
FORMIC ACIDFORMIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303