7FTM: Crystal Structure of human cyclic GMP-AMP synthase in complex with 2-[2-(4-fluoroanilino)-1,3-thiazol-4-yl]acetic acid

PDB ID: 7FTMDownload
MMDB ID: 242830
PDB Deposition Date: 2023/2/8
Updated in MMDB: 2026/02
Experimental Method:
x-ray diffraction
Resolution: 1.698  Å
Source Organism:
Similar Structures:
Biological Unit for 7FTM: monomeric; determined by author and by software (PISA)
Molecular Components in 7FTM
Label Count Molecule
Protein (1 molecule)
1
Cyclic Gmp-amp Synthase
(Gene symbol: CGAS)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
[2-(4-fluoroanilino)-1,3-thiazol-4-yl]acetic acid[2-(4-fluoroanilino)-1,3-thiazol-4-yl]acetic acid
2
1
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303