7FTL: Crystal Structure of human cyclic GMP-AMP synthase in complex with 8-chloro-2-(2-hydroxyphenyl)quinoline-4-carboxylic acid

PDB ID: 7FTLDownload
MMDB ID: 242829
PDB Deposition Date: 2023/2/8
Updated in MMDB: 2024/02
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
Similar Structures:
Biological Unit for 7FTL: monomeric; determined by author and by software (PISA)
Molecular Components in 7FTL
Label Count Molecule
Protein (1 molecule)
1
Cyclic Gmp-amp Synthase
(Gene symbol: CGAS)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
ZINC IONZINC ION
2
1
(2P)-8-chloro-2-(2-hydroxyphenyl)quinoline-4-carboxylic acid(2P)-8-chloro-2-(2-hydroxyphenyl)quinoline-4-carboxylic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303