7FS4: Structure of liver pyruvate kinase in complex with allosteric modulator 16

PDB ID: 7FS4Download
MMDB ID: 228808
PDB Deposition Date: 2022/12/18
Updated in MMDB: 2024/05
Experimental Method:
x-ray diffraction
Resolution: 2.19  Å
Source Organism:
Similar Structures:
Biological Unit for 7FS4: tetrameric; determined by author and by software (PISA)
Molecular Components in 7FS4
Label Count Molecule
Proteins (4 molecules)
4
Pyruvate Kinase Pklr
(Gene symbol: PKLR)
Molecule annotation
Chemicals and Non-standard biopolymers (19 molecules)
1
5
1,6-di-O-phosphono-beta-D-fructofuranose1,6-di-O-phosphono-beta-D-fructofuranose
2
4
OXALATE IONOXALATE ION
3
4
MAGNESIUM IONMAGNESIUM ION
4
4
POTASSIUM IONPOTASSIUM ION
5
2
4,4',5-trihydroxy-N-{[4-(3-hydroxybenzene-1-sulfonyl)phenyl]methyl}[1,1'-biphenyl]-2-sulfonamide4,4',5-trihydroxy-N-{[4-(3-hydroxybenzene-1-sulfonyl)phenyl]methyl}[1,1'-biphenyl]-2-sulfonamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303