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Biotechnology Information

7F4F: Cryo-EM structure of afamelanotide-bound melanocortin-1 receptor in complex with Gs protein and scFv16

PDB ID:

MMDB ID:

206296

PDB Deposition Date:

2021/6/18

Updated in MMDB:

2021/09

Experimental Method:

electron microscopy

Resolution:

2.9 Å

Source Organism:

synthetic construct▼

Taxonomy	Molecule
synthetic construct	S, F
Homo sapiens	R, A, G, B

Similar Structures:

Biological Unit for 7F4F: hexameric; determined by author

Molecular Components in 7F4F
Label	Count	Molecule
Proteins (6 molecules)
S	1	Scfv16
R	1	Melanocortin-1 Receptor
A	1	Guanine Nucleotide-binding Protein G(i) Subunit Alpha-1
G	1	Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
B	1	Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
F	1	Afamelanotide
Chemical and Non-standard biopolymers (1 molecule)
1	1	CALCIUM ION

* Click molecule labels to explore molecular sequence information.

Citing MMDB