7F4D: Cryo-EM structure of alpha-MSH-bound melanocortin-1 receptor in complex with Gs protein and Nb35

PDB ID: 7F4DDownload
MMDB ID: 206295
PDB Deposition Date: 2021/6/18
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 3  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 7F4D: hexameric; determined by author
Molecular Components in 7F4D
Label Count Molecule
Proteins (6 molecules)
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(o) Subunit Gamma-2
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i) Subunit Alpha-1
Molecule annotation
1
Nanobody 35
Molecule annotation
1
Guanine Nucleotide-binding Protein G(i)/g(s)/g(t) Subunit Beta-1
Molecule annotation
1
Melanocortin-1 Receptor
Molecule annotation
1
Alpha-melanocyte-stimulating Hormone
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
CALCIUM IONCALCIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303