7EKT: human alpha 7 nicotinic acetylcholine receptor bound to EVP-6124 and PNU-120596

PDB ID: 7EKTDownload
MMDB ID: 202126
PDB Deposition Date: 2021/4/6
Updated in MMDB: 2024/12
Experimental Method:
electron microscopy
Resolution: 3.02  Å
Source Organism:
Similar Structures:
Biological Unit for 7EKT: pentameric; determined by author
Molecular Components in 7EKT
Label Count Molecule
Proteins (5 molecules)
5
Neuronal Acetylcholine Receptor Subunit Alpha-7
(Gene symbol: CHRNA7)
Molecule annotation
Chemicals and Non-standard biopolymers (30 molecules)
1
15
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
5
CHOLESTEROLCHOLESTEROL
3
5
7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide7-chloro-N-(quinuclidin-3-yl)benzo[b]thiophene-2-carboxamide
4
5
N-(5-Chloro-2,4-dimethoxyphenyl)-N'-(5-methyl-3-isoxazolyl)-ureaN-(5-Chloro-2,4-dimethoxyphenyl)-N'-(5-methyl-3-isoxazolyl)-urea
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303