7EBH: Crystal structure of human pyruvate dehydrogenase kinase 2 in complex with compound 13

PDB ID: 7EBHDownload
MMDB ID: 205213
PDB Deposition Date: 2021/3/9
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.96  Å
Source Organism:
Similar Structures:
Biological Unit for 7EBH: dimeric; determined by author and by software (PISA)
Molecular Components in 7EBH
Label Count Molecule
Proteins (2 molecules)
2
[pyruvate Dehydrogenase (Acetyl-transferring)] Kinase Isozyme 2, Mitochondrial
(Gene symbol: PDK2)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
2
CHLORIDE IONCHLORIDE ION
2
4
ACETATE IONACETATE ION
3
4
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
4
2
5-bromanyl-2-methyl-6-propyl-7H-pyrrolo[2,3-d]pyrimidine5-bromanyl-2-methyl-6-propyl-7H-pyrrolo[2,3-d]pyrimidine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303