7EBB: Crystal structure of human pyruvate dehydrogenase kinase 4 in complex with compound 2

PDB ID: 7EBBDownload
MMDB ID: 205211
PDB Deposition Date: 2021/3/9
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 7EBB: dimeric; determined by author and by software (PISA)
Molecular Components in 7EBB
Label Count Molecule
Proteins (2 molecules)
2
[pyruvate Dehydrogenase (Acetyl-transferring)] Kinase Isozyme 4, Mitochondrial
(Gene symbol: PDK4)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
5
SULFATE IONSULFATE ION
2
1
1H-pyrrolo[2,3-b]pyridine-3-carbonitrile1H-pyrrolo[2,3-b]pyridine-3-carbonitrile
3
1
MAGNESIUM IONMAGNESIUM ION
4
1
ADENOSINE-5'-DIPHOSPHATEADENOSINE-5'-DIPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303