7E2E: Crystal structure of the Estrogen-Related Receptor alpha (ERRalpha) ligand-binding domain (LBD) in complex with an agonist DS45500853 and a PGC-1alpha peptide

PDB ID: 7E2EDownload
MMDB ID: 203752
PDB Deposition Date: 2021/2/5
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.7  Å
Source Organism:
Similar Structures:
Biological Unit for 7E2E: tetrameric; determined by author
Molecular Components in 7E2E
Label Count Molecule
Proteins (4 molecules)
2
Steroid Hormone Receptor Err1
(Gene symbol: ESRRA)
Molecule annotation
2
Peroxisome Proliferator-activated Receptor Gamma Coactivator 1-alpha
(Gene symbol: PPARGC1A)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
1-[4-(3-tert-butyl-4-oxidanyl-phenoxy)phenyl]ethanone1-[4-(3-tert-butyl-4-oxidanyl-phenoxy)phenyl]ethanone
2
1
IODIDE IONIODIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303