7DHL: Crystal structure of FGFR3 in complex with pyrimidine derivative

PDB ID: 7DHLDownload
MMDB ID: 198291
PDB Deposition Date: 2020/11/16
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.57  Å
Source Organism:
Similar Structures:
Biological Unit for 7DHL: monomeric; determined by author
Molecular Components in 7DHL
Label Count Molecule
Protein (1 molecule)
1
Fibroblast Growth Factor Receptor 3
(Gene symbol: FGFR3)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
5-[2-(3,5-dimethoxyphenyl)ethyl]-N-[3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]pyrimidin-2-amine5-[2-(3,5-dimethoxyphenyl)ethyl]-N-[3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]pyrimidin-2-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303