7DDH: Crystal structures of Na+,K+-ATPase in complex with digoxin

PDB ID: 7DDHDownload
MMDB ID: 198044
PDB Deposition Date: 2020/10/29
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 3.46  Å
Source Organism:
Similar Structures:
Biological Unit for 7DDH: trimeric; determined by author and by software (PISA)
Molecular Components in 7DDH
Label Count Molecule
Proteins (3 molecules)
1
Sodium/potassium-transporting Atpase Subunit Alpha-1
(Gene symbol: ATP1A1)
Molecule annotation
1
Sodium/potassium-transporting Atpase Subunit Beta-1
(Gene symbol: ATP1B1)
Molecule annotation
1
Fxyd Domain-containing Ion Transport Regulator
Molecule annotation
Chemicals and Non-standard biopolymers (18 molecules)
1
3
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
2
MAGNESIUM IONMAGNESIUM ION
3
1
SODIUM IONSODIUM ION
4
4
CHOLESTEROLCHOLESTEROL
5
7
1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
6
1
DIGOXINDIGOXIN
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303